BIO RAW MAT'L
Stem cell Assembloid for Regeneration
[Cord blood & Adipose ]
Stemcells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosi s)to produce more stem cells. They are found in ulticellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues.
In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm —but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.
There are three known accessible sources of autologous adult stem cells in humans:
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Bone marrow, which requires extraction by harvesting, that is, drilling into bone (typically the femur or iliac crest).
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Adipose tissue (lipid cells), which requires extraction by liposuction.
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Blood, which requires extraction through apheresis, wherein blood is drawn from the donor (similar to a blood donation), and passed through a machine that extracts the stem cells and returns other portions of the blood to the donor.
Stem cells can also be taken from
umbilical cord blood just after birth. Of all stem cell types, autologous harvesting involves the least risk. By definition, autologous cells are obtained from one's own body, just as one may bank his or her own blood for elective surgical procedures.
Adult stem cells are frequently used in medical therapies, for example in bone marrow transplantation. Stem cells can now be artificially grown and transformed (differentiated) into specialized cell types with characteristics consistent with cells of various tissues such as muscles or nerves. Embryonic cell lines and
autologous embryonic stem cells generated through Somatic-cell nuclear transfer or dedifferentiation have also been proposed as promising candidates for future therapies. Research into stem cells grew out of findings by Ernest A. McCulloch and James E. Till at the University of Toronto in the 1960s
Immuno cell Assembloid
[Natural killer, T-cell]
Immunology branch of biomedical science that covers the study of all aspects of the immune system in all organ isms. It deals with the physio logical functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immunedeficiency,
transplant rejection); the physical, chemical and physiological charact-eristics of the components of the immune system in vitro, in situ and in vivo. Immunology has applications in several disciplines of science, and as such is further divided. T-cell adoptive transf-er Adoptive cell transfer uses T cell-based cytotoxic responses to attack cancer cells. T cells that have a natural or genetically engineer ed reactivity to a patient's can cer are generated in vitro and then transferred back into the cancer patient. One study using autologous tumor-infil trating lymphocytes was an effective treatment for patients with metastatic elanoma;. This can be achieved by taking T- cells that are found with the tumor of the patient, which are trained to attack the cancerous cells. These T cells are referred to as tumor-infiltrating lympho cytes (TIL) are then encour-aged to multiply in vitro using high concentrations of IL-2, anti-CD3 and allo-reactive feeder cells. These T-cells are then transferred back into the patient along with exogenous administration of IL-2 to further boost their anti-cancer activity.
Microbiom Assembloid for Whitening, Atopic Solution
Natural Rutin is one of the phenolic compounds found in the invasive plant species Carpobrotus edulis and contributes to the antibacterial and antioxidant properties of the plant.While a body of evidence for the effects of rutin and quercetin is available in mice, rats, hamsters, and rabbits, as well as in vitro studies, no clinical studies directly demonstrate significant, positive effects of rutin as dietary supplement in humans.Rutin shows anti-inflammatory activity in some animal and in vitro models
Rutin inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body.Rutin is also an antioxidant; compared to quercetin, acacetin, morin, hispidulin, hesperidin, and naringin, it was found to be the strongest.[unreliable source?] However, in other trials, the effects of rutin were lower or negligible compared to those of quercetin.
